Thomas More s Utopia And Friedrich Engels Condition

Thomas More’s Utopia and Friedrich Engels Condition of the Working Class in England as two books provide extensive detail as well as insight on how societies and economies functioned earlier on throughout times. These books provide us with ideas that are still functionally applicable when we look to critique our current society and world economic system. They bring to attention what factors are paramount in the corruption and provide solutions that could aim to prevent or alter these societal ills. One of the first critique found in Utopia relates to ongoing theft and the misuse of their punishment system. â€Å"For this manner of punishing thieves goes beyond justice, and brings no public benefit: as a penalty for theft†¦show more content†¦This should not be in place as a preventive measure because it doesn t stop the actual problem, it just deals with the aftermath of crime. The real topic of interest should question why people need to resort to theft as a way of life. An issue that More also focused on dealt with the issues that came along an individual’s own vanity, and how it shields themselves from doing what s beneficial for the common good. When authoritative figures are negligent towards the importance of a country (means of national spending or labour of others to achieve personal short-term goals) it does not create any additional morale boost for the individuals living under said control. One’s greed could even cause cases of revolt within the people. â€Å" When he stated he would rather rule over the rich than be rich himself; and certainly, for some single person to indulge in pleasure and delights while surrounded by the weeping and lamentation of others is not to be the governor of a kingdom but of a gaol; finally, just as it’s a pretty useless as a doctor who only knows how to cure a disease by inflicting another one, so he who knows no other way to improve the lives of citizens except by taking away the amenities of life is admitting that he doesn’t know how to govern free men. Instead he ought to to curb either his sloth or hisShow MoreRelatedUtopia By Thomas More And The Condition Of The Working Class1881 Words   |  8 PagesRelates to Societies Hundreds of Years Ago The books, Utopia by Thomas More and the Condition of the Working Class by Friedrich Engels criticize societies hundreds of years ago, and upon reading these books, I have realized that our society today, shares many of the qualities of societies mentioned in these books. Utopia and the Condition of the Working Class brought to light the wealth gap and inequality within societies and how the conditions we are brought up in affects our future. The authorsRead MoreCommunism: Its Origins and World Impact Essay1025 Words   |  5 Pagescentury. It was Karl Marx and Friedrich Engels that began the theoretical foundation for the communist revolutions of the 20th century. Karl Marx founded the communist league in 1847. Karl Marx was born on May 5th 1818 and died on March 14th 1883. Marxs was born into a Jewish family who later converted to Christianity so his father could keep his job. Throughout his life he was a German economist, a philosopher and a revolutionist. He later joined up with Friedrich Engel (1820-1895). Together theyRead MoreCompare and Contrast Communism, Socialism, and Capitalism2094 Words   |  9 Pagesof resources. (5) Karl Marx and Friedrich Engels are the ones responsible for the theoretical foundations of the modern communism. In their time together Marx and Engels wrote several pieces of documentations and books which started in 1848 with The Communist Manifesto, 1850 Marx’s Class Struggles in France, 1867 The First Volume of Das Kapital, 1871 Civil War in France, 1875 Critique of the Gotha Programme, and in 1877 Engels so called Anti-Dà ¼hring. Marx and Engels took over and modified the currentRead MoreBranches of Philosophy8343 Words   |  34 Pages and its relation to various political systems[8]. In this period the crucial features of the philosophical method were established: a critical approach to received or established views, and the appeal to reason and argumentation. [pic] [pic] St. Thomas Aquinas [edit] Medieval philosophy (c. A.D. 500–c. 1350) Main article: Medieval philosophy Medieval philosophy is the philosophy of Western Europe and the Middle East during what is now known as the medieval era or the Middle Ages, roughly extendingRead MoreOne Significant Change That Has Occurred in the World Between 1900 and 2005. Explain the Impact This Change Has Made on Our Lives and Why It Is an Important Change.163893 Words   |  656 PagesWar, the victorious European powers appeared to have restored, even expanded, their global political and economic preeminence only to see it eclipsed by the emergence of the Soviet and U.S. superpowers on their periphery and a second round of even more devastating global conflict. The bifurcated international system that resulted from the cold war standoff extended the retreat of globalization, but nurtured the liberation of most of humanity from colonial rule. The collapse of the Soviet empire

Computer, Technology, and Society Essay - 1191 Words

Just think about how pervasive computers have become in our lives. In just a few short decades they appear to be everywhere: from our desktops, to our cars, to our coffeemakers and our phones. In the nineteen years from 1984 to 2003 the percentage of US households that have a computer in the home rose from 8.2% to 61.8%. From 1997 to 2009 the number of US households with Internet access at home climbed from 18% to 68.7%. As you can see the number of US households with a computer and Internet access in the home has skyrocketed over a relatively short time. Just a few years ago Americans could not call a neighbor on the telephone without the assistance of an operator. Parents would send letters and telegrams to their children away at†¦show more content†¦It is feared that the human mind will slowly lose its original ability to be creative due to many tasks that are now done by computers. Computers are now doing jobs previously done by hardworking individuals. What other tasks will be absorbed by computer technology in the future? Today, we enjoy a reliance on the Internet, e-shopping, e-trading and even e-therapy. E-everything is sweeping the nation. One of the many concerns is that humans will no longer need to relate with one another for information and services that the Internet can now provide. There is no doubt technology has and continues to have a profound effect on our society. The accelerating speed of the information superhighway should not replace human communication, thinking, or creativity. Our increasing dependence on computer technology must be well-balanced with face-to-face, human interaction and written correspondence. The human race deserves to retain its individuality separate from the technology we ourselves have created. We hold dominion over it. It does not claim dominion over us (Givens). The key phrase in the paragraph above is that our dependence on computer technology must be well-balanced. There are many arguments as to why spending an excessive amount of time on aShow MoreRelatedComputer Technology And Its Impact On Society Essay1168 Words   |  5 PagesComputer technology has evolved dramatically over the years and has significantly changed society. As technology advances, it transforms and improves society. Computer-related technology allows for enhancement of social functions previously difficult or impossible to execute. Computers have also accelerated productivity. Much less time is required nowadays to research information. Many in search of jobs and careers have reaped the rewards of computer technology. For too long, finding informationRead MoreComputer Technology and the Effects on Society1564 Words   |  7 PagesComputer Technology and the Effects on S Computer Technology and the Effect on Society Computer technology has had a great effect on society as a whole throughout history. It has modified our behavior greatly as we have become accustomed to the technological advancements of yesterday. We are so dependent sometimes we do not even have a concept of what life would be like without computers. When we are forced to live life without computers we are left hopeless and disillusioned and simple everydayRead MoreComputer Technology And Its Effect On Society1490 Words   |  6 Pagesfive years, computer technology, a digital device that automatically operates information and data, has been speedily varying and increasing in every field. It has brought many benefits to modern society. For example, technological advances will change society and home since there are many high technology systems will be installed, which will improve the quality of life. Communication become easier through one click because of the popularization of Inte rnet. Also, using computer technology will enhanceRead MoreComputer Technology And Its Impact On Society1195 Words   |  5 Pages In the early years of computers, engineers had to believe that their contribution to the development of computer technology would produce positive impacts on the people that would use it. During this period of infancy, ethical issues concerning computer technology were almost nonexistent because computers were not as multifaceted back then as they are today. Computer technology plays a crucial role in all aspects of our daily lives. Different forms of computer technology provide unique functionalitiesRead MoreHow The Society Values Computer Technology1716 Words   |  7 PagesName: Tubonemi Emmanuel Tamunobelema. Matric No: NS160014. Computer and the Society How the Society values Computer Technology Question: Google SDK/Artificial-Intelligence: Is it Good or bad? Table of Content 1.0 Introduction†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦1 1.1 My theory†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦2 1.2 Respondents opinions†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦5 2.0 Summary and Conclusion†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..10 Figures Fig 1.2.0 Do you interact with artificial intelligent systems? ............................Read MoreThe History and Technology of the Computer in the Nineteenth Century1590 Words   |  7 PagesIn our fast pace society, technology is ever changing. This has ultimately resulted in technology always being at our fingertips. On an average day so many people are dependent on computers for their capabilities; including, police officers, small businesses, Wall Street, and even the average person for leisure. Without the invention of the first mechanical computer design in 1822 by Charles Baggage, our society would not be where it is at today. The computer has been noted to be most of theRead MoreSocietys Addiction to Computers Essay781 Words   |  4 Pagesin technology, computers have developed to be the leader of the world. Increasingly, computers are playing more roles in helping people to remember a friend’s birthday or maintain relationships with others. Therefore, they h ave contributed positive to the development of relationships and improvement of the general knowledge of the society. Critics however argue that the society is becoming progressively more dependent on computers. In this essay, the arguments for the dependency on computers willRead MoreNext Came The Third Generation In 1963; In This Generation,1681 Words   |  7 Pages1963; in this generation, the computer became smaller, more influential, and more reliable and it was able to run lots diverse programs at the same time. Transistors were reduced and placed on silicon chips, called semiconductors, which hugely increased the speed and productivity of computers. Also, it s much smaller and cheaper compared to the second generation computers. Because of the various improvements to the development of the computer we have seen the computer being used in all areas of lifeRead MoreEffects Of Technology On Society s Society1246 Words   |  5 Pages Effects of Technology on Society Many years ago, historians believe the future would be an amazing technologically advanced place filled with robots and time traveling. But today no one seems to be shocked by all of the advancements (Negative Effects of Technology). The computers are controlling minds, and humans are acting more as robots than citizens. Over the last few decades, there has been a dramatic improvement in the development and use of technology. Workplaces have gone fromRead MoreTechnopoly: The Surrender of Culture to Technology by Neil Postman1120 Words   |  5 PagesAs time progresses technology increases and improves. However, this progression could pose as a serious problem for generations to come, and New York University department chair of communication arts Neil Postman expresses this concern in his 1992 book, Technopoly: The Surrender of Culture to Technology. In the opening of Postman’s book he expresses that technology is indeed our friend because technology provides our society with fast and easy convenience and accessibility. As with most other things

Law 421 Case Scenario Big Time Toymaker. Free Essays

Case Scenario: Big Time Toymaker. The parties did have a contract for exclusive negotiation rights as stated in the case scenario. Big Time Toymaker (BTT) paid Chou $25,000 for a 90-day period of exclusivity, thus prohibiting Chou from soliciting or entertaining offers from other parties. We will write a custom essay sample on Law 421 Case Scenario: Big Time Toymaker. or any similar topic only for you Order Now The agreement stipulated that unless it was written no distribution contract existed. Prior to the 90-days elapsing, the parties reached an oral agreement and BTT sent Chou an e-mail titled â€Å"Strat Deal† covering the key terms of the distribution agreement reaffirming the oral agreement. This e-mail does not constitute a contract for several reasons. First, this was part of the negotiation process and Chou failed to draft the contract to â€Å"memorialize† the deal. Second, the requirement of a signature is in compliance with the statute of frauds. This is the one element uniformly required to compel a court to enforce. Factors that weigh in for Chou are first, the e-mail sent by BTT’s manager clearly shows delineates the terms of the distribution agreement. Second, BTT’s request for the draft contract even after a month had elapsed. These actions go to show that BTT intended to continue the deal even after a month. Factors that weigh against are first, Chou failed to send the draft contract as he stated. Second, Chou assumed the e-mail sent by BTT took the place of a written distribution agreement contract. Third, he failed to follow up and get an agreement in writing signed. BTT’s e-mail to Chou caused further investigation in the analysis of the first two questions. First, the case scenario states the e-mail was sent by â€Å"a BTT manager,† not the chief executive officer or the like. The e-mail on its own is not sufficient to constitute â€Å"signed writings† within the meaning of Statute of Frauds. Last, the e-mail lacked the typed name of the person at BTT authorized to make the deal. BTT could not back out of the contract under the doctrine of mistake. Under this doctrine there has to be a misunderstanding that any of the parties erroneously believe that certain facts is true, or a common mistake shared by both parties (â€Å"Different Types of Lawyer,†Ã‚  2011). In this case no key misunderstanding existed and common mistake made that was operative. According to Melvin (2011),  consideration is most often when the offeror holds an offer open for a period. For arguments sake, and this e-mail constituted an agreement, the consideration would be the one month from Chou received the e-mail and the fax request from BTT. There are four remedies for breach of contract under UCC Article 2. Categorized as remedies of law; the first is compensatory damages, which cover direct losses and costs. Compensatory damages are an attempt to put the non-breaching party in the same position it would have been had they not suffered the breach. Second are consequential damages, which are to cover indirect and foreseeable losses not covered by compensatory damages. Third is restitution to prevent the unjust enrichment of one party in the agreement. Fourth, liquidated damages are provisions agreed to by the parties when drawing up the contract in the event of a default or breach of contract by either party (Melvin, 2011). Warranties come in two forms, either expressed or implied. The difference in the two is expressed warranties are stated and implied warranties are terms not discussed by the parties yet covered by the UCC. Examples of expressed warranties are often supplied with new automobiles or cell phones sold with lengthy, written, and specific warranties. An example of an implied warranty would be a mason who has become accustomed to the quality of brick his supplier has been providing. A violation of the implied warranty would be the consistency of the bricks changes, and the quality is not as good. Conclusion In conclusion, it is imperative that even if some company is willing to embark on an exclusive negotiation agreement does not signify 100% commitment. Both parties need to perform as agreed upon or an unpredictable outcome is possible, even litigation. The key to any relationship in business is communication throughout the process of a deal. Amicable negotiations are speedier and preferable to remedies at law. References Different Types of Lawyer. (2011). Retrieved from http://different-types-of-lawyers. blogspot. com/2011/12/contract-law-doctrine-of-mistake. html Melvin, S. P. (2011). The Legal Environment of Business. New York, New York: McGraw Hill/Irwin. How to cite Law 421 Case Scenario: Big Time Toymaker., Essays

Biomedical Engineering Bone Repair Tissue Engineering

Question: Discuss about the Biomedical Engineering for Bone Repair Tissue Engineering. Answer: Introduction A vibrant tissue with competency to cure, maintain and restructure itself is popularly known, as Bone of our body is really an ultimate smart tissue. The elaboration, conservation and restoration of this tissue depend on three categories of cell that are osteoblasts, osteocytes and osteoclasts. As per global context, there are roughly more than 100 million cases of bone defects each year leading to the requirement of bone repair procedures. The autologous and allogeneic bone grafts are traditional methods of bone repair but they persist certain limitations and poor outcomes. However, the advances of tissue engineering process in last few decades have increased the possibility of in vitro bone repair and regeneration (Enderle and Bronzino, 2012). In a simple understanding, tissue engineering is a combination of life sciences plus biological engineering approaches to develop biological substitutes. In comparison to traditional biomaterials approach the tissue engineering provide an advantage of innovative purposeful tissue construction instead only providing the implant of new replacement part making this technique an innovation in medical sciences (Reis and Cohn, 2012). Figure 1: General process of Bone tissue engineering (Source: Enderle and Bronzino, 2012,p.34) The dynamic qualities of bone and advance processes of bone tissue engineering show a great compatibility to overcome the persisting bone disorders. Currently, after blood, bone is the second tissue-engineering transplant forming a hope for medical science. But, still this technique also involves certain challenges (Enderle and Bronzino, 2012). In this essay, a detailed study on management and progress of tissue engineering in bone repair followed by the challenges and future aspects of this technique are done. Tissue engineering management and progress for repairing bone defects According to Amini et al. (2012), the specific goal of bone tissue contriving is to raise in vitro bone culture possibilities by applying innovative engineering approaches. In few recent decades, a wealthy progress is achieved in bone tissue engineering related to cell sources, biodegradable scaffolds, biocompatibility achievements, advanced bioreactors and identification of specific growth factors to produce bone in artificial conditions as well as natural conditions. The bone tissue engineering process simply involves three major aspects that involve processes to select stem cells, scaffolds formation and biological conditions development to achieve ideal, robust, reproductive and functional bone repair. Correia et al. (2012) studied that bone tissue engineering firstly involves the formation of scaffold that is a medium providing specific architecture and environment for tissue regeneration. There are various materials like ceramic, metals and polymers that are widely used for sca ffold formation until the emergence of biodegradable polymers. Bose et al. (2012) opine that there are natural occurring as well as artificially constructed biodegradable polymers that are ideal for scaffolds formation in tissue construction persisting properties like osteoinductivity, biodegradability, biological compatibility and porosity. The use of these biodegradable polymers in TE scaffolds formation is the most important achievement in bone tissue engineering process. The biodegradable scaffolds are formed from different materials that perform functionality with specific culture cells. Some of the most commonly used biodegradable scaffold materials are collagen, chitosan, starch, polyhydroxybutyrate, fibrin etc. A more determined biodegradable scaffolds are considered as the future trend in tissue engineering progress. Liu et al. (2013) studied that in initial times of tissue engineering the production of scaffolds remained a complex issue the traditional grafting technique provided less compatibility with biological materials. However, in recent times, the use of phase inversion, fibre bonding, high-pressure methods and freeze-drying are miracles in the tissue-engineering arena. Correia et al. (2012) opine the method of PLGA-poly (lactide-co-glycolide) scaffold formation using the phase inversion techniques. The scaffold produced through this technique is wide used in tissue engineering process. Figure 2: PLGA scaffold formation by using phase inversion technology (Source: Correia et al. 2012, p.2484) Further, the use of fibre bonding, injection moulding, melt-based technologies etc. is a progressive technique for scaffold formation. Amini et al. (2012) indicated that the limitations of using osteoblasts as an inducer of tissue engineering are overruled by the incoming of stem cells technology in artificial bone construction field. The use of stem cells is considered as most valid and promising solution for tissue making processes. Construction of bone from mesenchymal stem cell (MSCs) is one of the recent developments in tissue engineering field. The MSC being adult stem cells are widely present in bone marrow further named as BN-MSCs cells. These cells are widely used in tissue engineering to produce bone graft through applying technique of making artificial tissues in scaffolds that further undergo oestrogenic culture. Correia et al. (2012) further studied the practice of Adipose derived stem cells (ADSCs) in tissue making processes is another advantage because these stem cells have capabilities to critical size defects repair in both femoral and calvarial bone segment defects (Zhang et al. 2012). Bose and Tarafder (2012) studied the advances in bone tissue engineering by getting exceptional growth factors that work to produce in vitro bone cultures. The absence of effective growth factors limited the process of bone regenerations like cell adhesion, migration and differentiation. But, now the use of insulin growth factor III and platelet derived growth factor (PDGF), fibroblast growth factors (FGFs), bone morphogenetic proteins (BMPs),and transforming growth factor beta (TGF-) provides effective bone regeneration process. Further, Shin et al. (2012) indicated that the custom of bioreactors for making tissues artificially works as a new advancement to mimic the in vivo environment dynamics. These bioreactors are constructed to develop conditions and architectures that support tissue regeneration. Some of the most successful bioreactors till date are spinner flask bioreactor, static flask bioreactor, and rotating wall container bioreactors in bone tissue engineering. Figure 3: Static flasks, spinner flask and rotating wall vessel bioreactor used for in suit bone tissue construction (Source: Shin et al. 2012, p.260) The need of an experimental model to test the performance of technique is an essential component as well as limitation in biological research. Getting appropriate experimental models is a tough process in experimental science, Szpalski et al. (2012) stated that use of animal models is a new advancement to test the reliability of bone tissue engineering protocol. The experimental model should be feasible and should have high similarity index. Some of the most widely used animal models are subcutaneous model from rats and rabbit calvarial models that are widely used these days for testing the bone tissue engineering protocol. Tripathi and Basu (2012) studied that collaboration of gene therapy with bone tissue engineering helps to overcome the genetic defect along with bone disorder. The basic process involves delivery of specific proteins through viral vectors in the bone regeneration stages. Barriers in bone repair tissue engineering The bone tissue engineering process is the future of transplantation technology and is emerging as a new medical treatment approach but still it persist certain limitations that are holding back the progressiveness of this technology. Szpalski et al. (2012) studied that surgeon on everyday basis faces common challenges like reabsorption, infections, immunogenic reactions and insufficient vascularization while performing bone grafting in tissue engineering process. Liu et al. (2013) studied that bone tissue engineering is a highly expensive process that is not affordable on the regular basis due to an expensive high-quality bone, lack of donor, repeated failure of bone graft and use of expensive instruments. Making this technique cost-effective is becoming a challenge for scientists. Marolt et al. (2012) indicated in their study that failure of bone graft is a major challenge that is essential to get controlled in tissue regeneration process. The reason behind the failure of bone graf t still remains a mystery. Sometimes it is considered as a failure of appropriate biomaterial selection, wrong scaffold or improper in vitro conditions or growth factors delivery making the establishment of bone graft a challenge in technology. Szpalski et al. (2012) identified the confronts in artificial bone construction protocol that involves premature aging and differentiation of osteogenic cells, lack of control over cell viability and proliferation in 3D scaffolds, lack of knowledge on control parameters for cultivated human bone marrow behaviour under in vivo environment. Further, Liu et al. (2013) stated that in vivo transplantation of regenerated bone tissue is another barrier in establishing successful bone tissue engineering process. There are unknown biological processes that refuse the in vitro bone graft in animal model experiments. Future aspects in bone repair tissue engineering The bone tissue engineering technology is considered to be a complex and complicated structural arrangement process. There are different cell types, biomaterials, MSCs, growth factors and other factors that work together in this process. However, in last few decades, tissue engineering attained a considerable progress in utilizing bioactive factors, scaffolds development, getting potent cell source, suitable biomaterials and bioreactors. But now the future relies on overcoming the challenges of technique. Liu et al. (2013) studied that currently the shift of scientific minds is to develop improved vascular creation in this field if artificially created bones because it is the priority essential factor for graft existence. Nguyen et al. (2012) neo-bone tissue always survive in regions having the vascular network, therefore, it is important to induce vascularization under in vitro conditions of bone formation. Liu et al. (2013) stated that induction of angiogenesis and vasculogenesis is another future emerging theme because these processes work at in vivo conditions to develop new blood vessels. The development of artificial angiogenesis and vasculogenesis will help to control the in vivo graft rejection. Therefore, it is another important future aspect of bone tissue engineering process. According to Szpalski et al. (2012), there are on-going researches to establish scaffold that promotes vascular formation. Marolt et al. (2012) studied the research is done to utilize stem cells for neo-vascularisation where endothelial progenitor/stem cells are been utilized for generating vascularized bone graft by co-culture systems and combined linkages with osteogenic cells in different scaffolds to produce neo-vascularisation as a future trend in bone tissue construction process. Conclusion In present era, there is essential requirement of effective clinical treatments for severe bone defects at global scenario but there are limitations in established technologies like autograft and allograft. In last two decades that has been a remarkable positive progress in bone tissue engineering process annually making it a hope for getting better clinical treatment for bone repair. In the recent times there are remarkable achievements in bone tissue engineering procedures and technologies but still this field of medical science is in its developing state. More concentration is required to overcome the deficits in technologies like better scaffolds, more effective bioreactors, better stabilizing enzymes and laboratory condition to get 100% in suit transplantation or bone grafting done successfully. Tissue engineering holds a promising approach to provide better medical treatment for disease like cancer, diabetes etc. which are still in incurable state. The so far success for this technique is encouraging, whereas the challenges and future aspects are giving this technology a new height in clinical application. It is expected that in near future tissue engineering will acquire a successful in vivo bone graft transplantation and bone fracture repair treatment. References Books Enderle, J.D. and Bronzino, J.D., 2012.Introduction to biomedical engineering. Academic press. Reis, R.L. and Cohn, D., 2012.Polymer based systems on tissue engineering, replacement and regeneration(Vol. 86). Springer Science Business Media. Journals Amini, A.R., Laurencin, C.T. and Nukavarapu, S.P., 2012. Bone tissue engineering: recent advances and challenges.Critical Reviews in Biomedical Engineering,40(5). Bose, S., Roy, M. and Bandyopadhyay, A., 2012. Recent advances in bone tissue engineering scaffolds.Trends in biotechnology,30(10), pp.546-554. Bose, S. and Tarafder, S., 2012. Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: a review.Acta biomaterialia,8(4), pp.1401-1421. Correia C, Bhumiratana S, Yan LP, Oliveira AL, Gimble JM, Rockwood D, Kaplan DL, Sousa RA, Reis RL, Vunjak-Novakovic G. 2012. Development of silk-based scaffolds for tissue engineering of bone from human adipose-derived stem cells. Acta biomaterialia, 8(7), pp.2483-92. Liu, Y., Lim, J. and Teoh, S.H., 2013. Review: development of clinically relevant scaffolds for vascularised bone tissue engineering.Biotechnology advances,31(5), pp.688-705. Marolt, D., Campos, I.M., Bhumiratana, S., Koren, A., Petridis, P., Zhang, G., Spitalnik, P.F., Grayson, W.L. and Vunjak-Novakovic, G., 2012. Engineering bone tissue from human embryonic stem cells.Proceedings of the National Academy of Sciences,109(22), pp.8705-8709. Nguyen, L.H., Annabi, N., Nikkhah, M., Bae, H., Binan, L., Park, S., Kang, Y., Yang, Y. and Khademhosseini, A., 2012. Vascularized bone tissue engineering: approaches for potential improvement.Tissue Engineering Part B: Reviews,18(5), pp.363-382. Shin, S.H., Purevdorj, O., Castano, O., Planell, J.A. and Kim, H.W., 2012. A short review: recent advances in electrospinning for bone tissue regeneration.Journal of tissue engineering,3(1), pp. 260-65. Szpalski, C., Wetterau, M., Barr, J. and Warren, S.M., 2012. Bone tissue engineering: current strategies and techniquespart I: scaffolds.Tissue Engineering Part B: Reviews,18(4), pp.246-257. Szpalski, C., Barbaro, M., Sagebin, F. and Warren, S.M., 2012. Bone tissue engineering: current strategies and techniquespart II: cell types.Tissue Engineering Part B: Reviews,18(4), pp.258-269. Tripathi, G. and Basu, B., 2012. A porous hydroxyapatite scaffold for bone tissue engineering: Physico-mechanical and biological evaluations.Ceramics International,38(1), pp.341-349. Zhang, Z.Y., Teoh, S.H., Hui, J.H., Fisk, N.M., Choolani, M. and Chan, J.K., 2012. The potential of human fetal mesenchymal stem cells for off-the-shelf bone tissue engineering application.Biomaterials,33(9), pp.2656-2672.